Retrieved sources were further explored applying both the snowball approach Table 1. Cystatin C (CysC) reference values as reported in literature in full term. A cistatina C tem sido proposta com um marcador alternativo da filtração em relação à creatinina. O presente estudo foi conduzido com o objetivo de avaliar o . Request PDF on ResearchGate | La cistatina C aporta más información que otros parámetros de función renal en la estratificación del riesgo.

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Serum cystatin C was determined by nephelometry and creatinine by modified Jaffe method. You can change the settings or obtain more information by clicking here. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

Highest rate of coronary artery disease CAD was seen Groups 1 and 2.

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Centro Hospitalar Lisboa Norte. The emerging role of serum cysC as a marker of cardiovascular disease severity and drug elimination may broaden the clinical use of this valuable cistatia.

Glucocorticoids and increased serum cystatin C concentrations.


Serum creatinine concentration is an imperfect measure of GFR. Albuminuric and non-albuminuric pathways to renal impairment in diabetes. A preliminary study on leukemia. In this study, Cystatin C revealed as a promisor marker of renal function in patient with lupus, mainly in patients with lower glomerular filtration rates.


In both studies, high serum cystatin C level is associated with the previous coronary heart disease.

Cystatin C: A Promising Marker of Renal Function in Patients with Systemic Lupus Erythematosus?

Arch Gerontol Geriatr ; Cystatin C and mortality risk in the elderly: Bienvenido a siicsalud Contacto Inquietudes. Patients with type 2 diabetes mellitus without known overt diabetic nephropathy were included in the study. How to cite this article. Increased renal production of transforming growth factor-beta1 in patients with type II diabetes.

Clinical usefulness of cystatin C for the estimation of glomerular filtration rate in type 1 diabetes: Biochem J ; J Endocrinol Invest ; The area under the curve in ROC analysis was found as A promising marker of glomerular filtration rate to replace creatinine.

Although urinary albumin excretion is suggested for detection of type 2 diabetic nephropathy, there is group of patients with decreased eGFR but without increased urinary albumin excretion, in which serum cystatin C level was indicated to be used as an early biomarker of diabetic nephropathy.

Serum cystatin C: a practical alternative for renal function evaluation?

The most important limitation of our study is the estimation of GFR measurements. Am J Kidney Dis ; N Engl J Med ; Nephrol Dial Transplant ; Clin Nephrol ; In the study of Yang and friends, serum cystatin C level showed correlation with MA level. When we consider the relation between serum cystatin C and serum creatinine levels and MDRD in whole study population we determined that the predictive ability of serum creatinine for GFR was higher.


J Am Soc Nephrol ; Freshly voided early morning urine samples were also collected for urinalysis. Clin Chem Lab Med ; Assessing kidney function – measured and estimated glomerular filtration rate. Is the Chronic Kidney Disease epidemiology Collaboration creatinine-cystatin C equation useful for glomerular filtration rate estimation in the elderly?

Cystatin C has been pointed as an alternative, but it was not tested in many diseases. We compared five formulas: Epub ahead of print Aug Si continua navegando, consideramos que acepta su uso.

Cystatin C identifies chronic kidney disease patients at higher risk for complications. Clin Chem ; Risch Cistatiina, Huber AR. In the study of Surendar et al. Vantagens e desvantagens desse marcador foram aqui discutidas.

O gene que codifica a cistatina C foi sequenciado e localiza-se no cromossomo We sought to determine whether it is a marker of renal function different from creatinine cystatin C potentially superior to creatininein patients with systemic lupus erythematosus.