Apidra SoloStar Units/ml solution for injection in a pre-filled pen – Patient The Patient Information Leaflet (PIL) is the leaflet included in the pack with a. Apidra SoloStar Units/ml solution for injection in a pre-filled pen . SoloStar, the Instructions for use included in the Package leaflet must be read carefully. APIDRA [insulin glulisine injection (rDNA origin)] is a recombinant . package insert, and the pump manufacturer’s manual (see DOSAGE AND.

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Linezolid is a reversible, nonselective MAO inhibitor and other MAO inhibitors have apifra associated with hypoglycemic episodes in diabetic patients receiving insulin or oral hypoglycemic agents. Beta-blockers also exert complex actions on the body’s ability to regulate blood glucose.

Apidra SoloStar 100 Units/ml solution for injection in a pre-filled pen

To prepare a dose from a vial: Contents of the pack and other information What Apidra contains The active substance is insulin glulisine. If you are not able to use SoloStar or follow all the instructions completely on your own, you must use SoloStar only if you have help from a person who is able to follow the instructions completely. Dispose of the needle safely, as instructed by your doctor, pharmacist or nurse. Systemic and inhaled corticosteroids are known to increase blood glucose and worsen glycemic control in patients taking antidiabetic agents.

Aggravation of diabetes mellitus has been reported.


You should know these factors so that you are able to react correctly to changes in your blood sugar level and to prevent it from becoming too high or too low.

Regular insulin, unlike insulin glulisine, is preferred for those patients with poor tissue perfusion, shock, or cardiovascular collapse, or in patients requiring insulin for the treatment of hyperkalemia. A marked change improvement or worsening in your blood sugar control can disturb your vision temporarily.

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If hypoglycemia occurs, discontinue or decrease the dose of the antidiabetic agent or discontinue the linezolid therapy. In addition, packaye use of inhaled insulin is not recommended ihsert patients who smoke. Animal data indicate that MAOIs may stimulate insulin secretion. Insulin is filtered and reabsorbed by the kidneys; the plasma half-life of human endogenous insulin is approximately 5—6 minutes. The American Diabetes Association recommends that regular insulin by continuous intravenous infusion be used to treat hyperglycemic crisis including diabetic ketoacidosis DKA and hyperosmolar hyperglycemic state HHS and diabetic coma unless it is considered mild.

Monitor for loss of glycemic control when pseudoephedrine, phenylephrine, and other sympathomimetics are wpidra to patients taking antidiabetic agents.

Insulin glulisine may be used in combination with oral agents e.

Fast-Acting, Mealtime Insulin | Apidra® (insulin glulisine [rDNA origin] injection)

Preparation and Administration Instructions for Patients: The physiologic response resulting from the mixing together of different insulins for subcutaneous administration may differ from the response occurring when the insulins are administered separately. SoloStar is a pre-filled pen for the injection of insulin. Following subcutaneous administration, inssrt glulisine has an onset of action of approximately 20 minutes which is more rapid than the onset of regular insulin.


Active ingredient insulin glulisine. Do not use insulin glulisine that oackage been frozen.

Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. Limited data are available regarding the pharmacokinetics of intravenously administered insulin glulisine. Only regular insulin, insulin lispro, insulin glulisine, and insulin aspart should be used for continuous subcutaneous insulin infusion CSII administration in external pumps.

Insulin requirements are highly variable and must be individualized based on patient-specific factors and type of insulin regimen.

Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. Do not pass it on to others. Do not use this SoloStar if the insulin is cloudy, coloured or has particles.

Select the dose You can set the dose in steps of 1 unit, packag a minimum of 1 unit to a maximum of 80 units. Dosage adjustments may be necessary.

Storage of infusion bags: Follow recommended safety measures for removal and disposal of needles contact your doctor, pharmacist or nurse in order to reduce the risk of accidental needle injury and transmission of infectious diseases.